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 Antigen Presenting Cells: From Mechanisms to Drug Development
This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system. ... | | Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease
This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology.
The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The... | | Design of Experiments in Chemical Engineering: A Practical GuideWhile existing books related to DOE are focused either on process or mixture factors or analyze specific tools from DOE science, this text is structured both horizontally and vertically, covering the three most common objectives of any experimental research:
- screening designs
- mathematical modeling, and...
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Leukocyte Trafficking: Molecular Mechanisms, Therapeutic Targets, and Methods
Written by known specialists in the field, this is a comprehensive and timely overview of a central and expanding topic. Simultaneously an introduction and a description of the latest concepts, findings and methods, the handbook provides basic knowledge on technical issues required for those intending to research in the field. It covers the... | | Analogue-based Drug Discovery
The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum... | | Immunodominance
The normal, intact immune system does not have equal probability of responding
to every potential part of a protein. It has been known for more than 50 years that
only parts of the protein that are “outside” are available for antibody binding. Yet,
with the advent of Western blotting techniques, antibodies that react... |
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