"This treatise on bioinformatics is an excellent reference set to use as additional reading in advanced undergraduate and graduate courses..." (ChemMedChem, October 2007)
Once again, Thomas Lengauer has succeeded in creating a comprehensive and immensely useful resource that meets even the high...
This completely revised second edition of the standard work has been expanded by some twenty percent to include more information on the latest developments and new apparatus. In particular, sections have been added on microplasmas and new types of spectrometers, while that on the rapidly expanding field of speciations with practical examples...
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical...
This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to...
A relativistic consistent quantum-theoretical description of electronic bound states in atoms was first introduced in atomic physics as early as the late 1920s and has been pushed forward since that time. It was believed, however, that effects stemming from Einstein’s theory of relativity were of little or even no importance to chemistry....
A complete update of the highly acclaimed handbook with data on all neurotransmitters and the majority of neuromodulators. The coverage is now even more comprehensive, with 15% more entries on neuropeptides, "classic" neurotransmitters and related substances in a clear, alphabetical format. The methodological section has been...
Ceramic Matrix Composites (CMCs) represent a relatively new class of quasiductile
ceramic materials. They are characterized by carbon or ceramic fi bers embedded
in ceramic matrices (oxide or non - oxide) with comparatively low bonding
forces between the fi bers and the matrix. These weak intefaces, in combination
with a porous...
In this, the only up-to-date book on this key technology, the number-one expert in the field perfectly blends academic knowledge and industrial applications.
Adopting a didactical approach, Professor Ronda discusses all the underlying principles, such that both researchers as well as beginners in the field will profit from this book. The...
This first ever coverage of the pharmacokinetic and pharmacodynamic characteristics of biopharmaceuticals meets the need for a comprehensive book in this field. It spans all topics from lead identification right up to final-stage clinical trials.
Following an introduction to the role of PK and PD in the development of biotech...
Explosives and propellants contain considerable chemical energy that can be converted into rapid expansion. In contrast to the simple burning of a fuel, explosives and propellants are self-contained and do not need an external supply of oxygen via air. Since their energy content inherently creates the risk of accidental triggering of the...
The introduction of the matrix-assisted laser desorption ionization technique (MALDI) changed mass spectrometry (MS) into a powerful tool for biomedical analysis that is now widely employed in academic as well as industrial laboratories.
The 2002 Nobel Prize was awarded for the development of methods for identification and...
This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed...
