The mechanism by which cigarette smoke causes or contributes to inflammatory diseases like chronic obstructive pulmonary disease, cardiovascular disease and cancer remains unclear. Recent developments in our knowledge of cellular signaling suggest that cigarette smoke may cause oxidative stress in cellular systems. The assessment,...

Expectations of the potential of regenerative medicine have risen recently because of exciting research results. This book contains contributions from leading researchers who describe their successes and the problems that remain in converting the hopes into concrete therapies. The focus of the book is on the role of stem cells in two main...

"Kernel Based Algorithms for Mining Huge Data Sets" is the first book treating the fields of supervised, semi-supervised and unsupervised machine learning collectively. The book presents both the theory and the algorithms for mining huge data sets by using support vector machines (SVMs) in an iterative way. It demonstrates how kernel...

This book deals with the main control aspects in underwater manipulation tasks. The mathematical model with significant impact on the control strategy is discussed. The problem of controlling a 6-degrees-of-freedoms autonomous underwater vehicle is deeply investigated and a survey of fault detection/tolerant strategies for unmanned underwater...

Experimentation is necessary - a purely theoretical approach is not reasonable. The new experimentalism, a development in the modern philosophy of science, considers that an experiment can have a life of its own. It provides a statistical methodology to learn from experiments, where the experimenter should distinguish between statistical...

Defining a formal domain ontology is generally considered a useful, not to say necessary step in almost every software project. This is because software deals with ideas rather than with self-evident physical artefacts. However, this development step is hardly ever done, as ontologies rely on well-defined and semantically powerful AI concepts...