Diabetes mellitus and its complications are conditions of growing importance from both the clinical and epidemiological standpoint. Diabetes has life-threatening complications affecting several organs and systems, with increased risk for ocular, renal, cardiac, cerebral, nervous and peripheral vascular disease. In many developed countries and...

This volume discusses radiotherapy and its role in the treatment of benign diseases. Its intent is to broaden the application of radiotherapy beyond malignancy to treat a range of clinical concerns, from minor skin problems to life-threatening arterial disease. In addition, it aims to encourage medical practitioners to consider the benefits...

This is the only comprehensive collection of algorithms which exclusively addresses hematologic and oncologic problems affecting neonates, children and adolescents. Examining clinical problems which challenge the pediatrician, general practitioner and family practice physician, each algorithm utilizes a concise, step-by-step approach based...

The objective of this publication is to enhance mutual understanding and communication between ophthalmologists, molecular geneticists, genetic counselors and biomedical researchers. In the introductory chapter, current genetic paradigms and experimental genetic approaches relevant to the nature of hereditary disorders are discussed. The...

The cytological diagnosis of soft tissue tumours, based on fine needle aspirates, has been debated and at times dis couraged except in the diagnosis of lipoma. Soft tissue tumours are relatively rare in spite of the fact that more than 100 benign subtypes, over 50 variants of sarcoma and a number of 'border-line' entities have been...

Group A streptococcal pharyngitis is one of the most common, but also controversial infections clinicians are faced with every day. Clinical diagnosis is often not specific; laboratory data can be misleading and are frequently misinterpreted. Despite the in vitro effectiveness of penicillin, it does not always eradicate the organism from the...

Visual dysfunction is prevalent in Alzheimer’s disease and in related disorders such as posterior cortical atrophy and Down syndrome. The neuropathology of these disorders affects brain areas that process low-level vision as well as higher-order cognition and attention. This volume spans the range of topics on vision, from structure...

Diabetes mellitus is one of the most frequent chronic diseases affecting children and adolescents. The number of young children being diagnosed with type 1 diabetes is increasing worldwide and an epidemic of type 2 diabetes already at a young age is being observed in most societies around the world. In this book, leading experts from the USA,...

Over the past decades many surgical subspecialties have moved from traditionally open procedures towards minimally invasive approaches. With the advent of improved technology and smaller more maneuverable devices more delicate procedures have been developed. In this volume the most common neuroendovascular procedures currently practiced are...

The future of neurosurgery will be characterized by less invasive, molecular technologies that promise to revolutionize the field of neurosurgery and impact the treatment of additional neurological disorders, including neurometabolic diseases, stroke, dementias, affective and psychiatric diseases, movement disorders, epilepsy, and others....

In the western world, the prevalence of allergy and asthma has increased two- to threefold over the last 40 years and has reached epidemic proportions. This book represents the first complete document containing recommendations on the prevention of allergy and allergic asthma based on the current understanding of the immunological mechanisms...