Cancer and other genetic human diseases are caused by a variety of mutations, ranging from subtle sequence changes to larger genomic rearrangements and alterations in chromosome number (aneuploidy). With contributions by reputed experts, this book aims to update the knowledge on the multiple mechanisms of genomic instability leading to human...
Coaching is more than simply learning a process and set of skills. Exceptional coaches draw on their professional experience, knowledge of organizationally relevant topics, strong helping skills, coaching-specific competencies, and most important, their ability to use their own intuition in the service of the client. "Becoming an...
Our understanding of how the human brain performs mathematical calculations is far from complete, but in recent years there have been many exciting breakthroughs by scientists all over the world. Now, in The Number Sense, Stanislas Dehaene offers a fascinating look at this recent research, in an enlightening exploration of the...
Digital media has exploded over the past quarter century, and in particular the past decade. As varieties of digital media multiply, scholars are beginning to examine its origins, organization, and preservation, which present new challenges compared to traditional media. To examine issues from multiple perspectives, experts...
This reference work looks at modern concepts of computer security. It introduces the basic mathematical background necessary to follow computer security concepts before moving on to modern developments in cryptography. The concepts are presented clearly and illustrated by numerous examples. Subjects covered include: private-key and public-key...
The last two decades have shown that the local microenvironment plays a pivotal role in cancer progression. Cancer is not the result of mutation events in single cells, but of a complex interplay of tumor cells, inflammatory cells, stem cells, growth factors, cytokines, chemokines and DNA-damaging agents. This book provides an up-to-date...
Over the past decades many surgical subspecialties have moved from traditionally open procedures towards minimally invasive approaches. With the advent of improved technology and smaller more maneuverable devices more delicate procedures have been developed. In this volume the most common neuroendovascular procedures currently practiced are...
The importance of equational axioms emerged initially with the axiomatic approach to Boolean algebras, groups, and rings, and later in lattices. This unique research monograph systematically presents minimal equational axiom-systems for various lattice-related algebras, regardless of whether they are given in terms of join and meet or other...
Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. This book provides detailed and updated information on the role of these molecules in cancer. It is the first to summarize current knowledge of the importance of protein precursors maturation by the convertases in tumor...
This book contains an up-to-date review of diagnostic and staging tools of cholangiocarcinoma, a guide to optimal selection of therapeutic modalities and a review of long-term outcome of surgery and liver transplantation. It also provides surgical techniques and principles for curative and palliative surgery. This book will appeal to...
Through the combination of the latest imaging modalities and microdevice delivery, interventional neuroradiologic techniques are currently revolutionizing the therapy for many of the most common neurological and neurosurgical disorders. Crossing the boundaries of classically delineated medical and surgical specialties including neurosurgery,...
The intestine is the front line of the confrontation between pathogens and the immune system. However, it is also important to emphasize that we have a symbiotic relationship with innumerable bacteria in the intestine. In the gastrointestinal tract of mammals the lower intestine harbors around 1,000 12 species of anaerobic and aerobic...
