This volume reviews advances in cancer chemotherapy research over the last 10 years. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs. Each chapter covers the drug target and biological rationale, chemotypes, clinical status and future prospects in this...
The SQL Server Query Optimizer is perceived by many to be a magic black box, transforming SQL queries into high performance execution plans in the blink of an eye through some unknowable process. The truth is that, while the Query Optimizer is indeed the highly-complex result of decades of research, learning how it works its magic is not only...
From the founders of the trailblazing software company 37signals, here is a different kind of business book - one that explores a new reality. Today, anyone can be in business. Tools that used to be out of reach are now easily accessible. Technology that cost thousands is now just a few pounds or even free. Stuff that was impossible just a...
An original workbook companion to the acclaimed business bestseller The Back of the Napkin
Dan Roam's The Back of the Napkin, a BusinessWeek bestseller, taught readers the power of brainstorming and communicating with pictures. It presented a new and exciting way to solve all kinds of...
This book highlights proteasome structures and how they are related to different aspects of proteasome function. Moreover, the book reports on the functional roles these highly developed proteolytic machines play within the cell. It was a great surprise to the scientific world that proteolysis provides crucial functions in cellular...
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This book describes how marketing organizations successfully move from product concept to the creation of a successful brand, and explains the key tools used to develop branding. It introduces selling theories and the principles of consumer behaviour, and documents the creation and development of brands using real-world examples. It goes on...
PUBLIC SPEAKING: THE EVOLVING ART is the first book and integrated technology package to meet the expectations of today's students while both preserving and offering innovative variations on the well-respected traditions of public speaking instruction. Throughout the text, readers benefit from the examples of four peer mentors--real...
Powered by intellect, driven by values Infosys has been at the forefront of a new India Inc. since 1981. Leadership @ Infosys is the first book to codify Infosys s unique history, values and leadership practices that account for the firm s stellar rise from US$ 200 seed capital to a multibillion dollar global enterprise. As an extension of...
Several problems in modern genome mapping analysis belong to the field of discrete optimization on a set of all possible orders. In this book, formulations, mathematical models and algorithms for genetic/genomic mapping problem that can be formulated in TSP-like terms are proposed.
clear exposition and the consistency of presentation make learning arithmetic accessible for all. Key concepts are presented in section objectives and further defined within the context of How and Why; providing a strong foundation for learning. The predominant emphasis of the book focuses on problem-solving, skills, concepts, and...
Today's sales managers have to be quicker than ever, being more proactive about hiring the best performers and retaining them, multi-tasking, and managing complex sales processes in order to close more and more deals. This book provides readers with a proven method for managing the sales process as well as the salespeople. Packed with...
