Exploring innovative routes of drug discovery in the postgenomic era, Microbial Genomics and Drug Discovery examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of new antibacterial targets and vaccine candidates. The book discusses potential pathways for effective infection control,...

Stressing major themes in the history of medicine, this Second Edition stimulates further exploration of the events, methodologies, and theories that shaped medical practices in decades past and in modern clinical practice-highlighting the practices of civilizations around the world, as well as the research of pioneering scientists and...

The definitive text on the state-of-the-art in pediatric trauma care, this reference offers detailed descriptions of procedures in system design, pediatric resuscitation, supportive care, diagnostic imaging, pain management, and transfusion therapy by experts with hands-on experience in the field. Providing evidence-based recommendations, as...

In addition to communicating current methods for diagnosis and assessing the array of conventional and newfound therapeutic options for dry eye and ocular surface disorders, this edifying reference offers scientific background on normal ocular surface and tear film functioning; descriptions of the mechanisms involved in inflammation; and a...

This book compiles state-of-the-art statistical approaches to solving problems in clinical oncology, focusing on clinical trials in phases I, II, and III, as well as quality of life and economic analyses, and exploratory methods.
Examines trial design treatment based on toxicity and survival!
Featuring over 1000 references,...

Evidence shows that nutritional supports can help maintain health in the HIV-infected patient by replacing lost nutrients, compensating for nutritional damage done by the retrovirus-induced immunodeficiency, and stimulating the remaining immune system and cells for better host defenses.

This new edition of Nutrition and AIDS...

The mechanical properties of whole bones, bone tissue, and the bone-implant interfaces are as important as their morphological and structural aspects. Mechanical Testing of Bone and the Bone-Implant Interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone-implant interface for bone-related...

Richly illustrated and easy to use, Myelopathy, Radiculopathy, and Peripheral Entrapment Syndromes presents extensive and up-to-date information about the etiopathic and clinical presentation of neurovascular compression insult to the spinal cord, spinal nerve roots, and peripheral nerves. Written with both the student and practitioner in...

It was once assumed that mitochondrial diseases were rare and that few people were affected. As knowledge has grown about these organelles and their function, it became clear that mitochondrial malfunction could be linked to several chronic diseases. Diabetes has been associated with DNA mutation and can cause mutation itself. This text...

Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular...