This is the first book to cover every angle in the clinical application of biologics. Readers will not only find that all of the biologics currently approved for clinical use are delineated in a standardized way, but also the "differential therapy" with biologics in fields including dermatology and neurology is described in detail...
Research over the past decades has firmly established the genetic basis of cancer. In particular, studies on animal tumour viruses and chromosome rearrangements in human tumours have concurred to identify so-called ‘proto-oncogenes’ and ‘tumour suppressor genes’, whose deregulation promotes carcinogenesis. These...
Many bacterial ADP-ribosyltransferases are potent bacterial protein toxins and important
virulence factors. After cellular uptake caused by highly efficient cell entry mechanisms,
they modify eukaryotic target proteins with great specificity and often grossly affect biological
functions of their targets. These properties of the...
There was a time not so long ago, well within the memory of many of us, when medical
imaging was an analog process in which X-rays, or reflected ultrasound signals,
exiting from a patient were intercepted by a detector, and their intensity depicted as
bright spots on a fluorescent screen or dark areas in a photographic film. The...
As other complex systems in social and natural sciences as well as in engineering, the Internet is hard to understand from a technical point of view. Packet switched networks defy analytical modeling. The Internet is an outstanding and challenging case because of its fast development, unparalleled heterogeneity and the inherent lack of...
Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. This hugely important new book describes the current knowledge of acute leukemia biology and discusses new classification systems that have arisen as a result of emerging insights into pathogenesis....
VLSI for Wireless Communication, Second Edition, an advanced level text book, takes a system approach starting with an overview of the most up to date wireless systems and the transceiver architecture available today. Wireless standards are first introduced (updated to include the most recent 3G/4G standards in the second edition), and...
However, in compiling a volume titled “DATA MINING: Foundations and Intelligent Paradigms: Volume 3: Medical, Health, Social, Biological and other Applications” we wish to introduce some of the latest developments to a broad audience of both specialists and non-specialists in this field.
Pervasive healthcare is an emerging research discipline, focusing on the development and application of pervasive and ubiquitous computing technology for healthcare and wellness. Pervasive healthcare seeks to respond to a variety of pressures on healthcare systems, including the increased incidence of life-style related and chronic diseases,...
This volume, a reprint from a special issue of the Journal of Nanoparticle Research, draws on work presented at The Second International Symposium on Nanotechnology and Occupational Health, held in Minnesota in 2005. It presents an interdisciplinary approach to nanotechnology and occupational health and offers an overview of recent...
For the first time, this book offers a critical review of the calcification process of the organic and inorganic phases of mineralized tissues focusing on the earliest phases. It includes a methodological chapter which provides the necessary practical information for making appropriate choices. The book is set to become an important reference...
The recent advances in neuroimaging techniques, particularly magnetic re- nance (MR), have greatly improved our knowledge of brain anatomy and related brain function. Morphological and functional investigations of the brain using high-definition MR have made detailed study of the brain possible and provided new data on anatomo-functional...