This volume presents an extensive collection of contributions covering aspects of the exciting and important research field of data mining techniques in biomedicine. Coverage includes new approaches for the analysis of biomedical data; applications of data mining techniques to real-life problems in medical practice; comprehensive...

The concept of 'shape' is at the heart of image processing and computer vision, yet researchers still have some way to go to replicate the human brain's ability to extrapolate meaning from the most basic of outlines. This volume reflects the advances of the last decade, which have also opened up tough new challenges in...

Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical...

Computational optimization is an important paradigm with a wide range of applications. In virtually all branches of engineering and industry, we almost always try to optimize something - whether to minimize the cost and energy consumption, or to maximize profits, outputs, performance and efficiency. In many cases, this search for...

The research of Antanas Zilinskas has focused on developing models for global optimization, implementing and investigating the corresponding algorithms, and applying those algorithms to practical problems. This volume, dedicated to Professor Zilinskas on the occasion of his 60th birthday, contains new survey papers in which leading...

This comprehensive textbook on combinatorial optimization places special emphasis on theoretical results and algorithms with provably good performance, in contrast to heuristics. It is based on numerous courses on combinatorial optimization and specialized topics, mostly at graduate level. This book reviews the...