In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. The authors provide exciting and enlightening perspectives on COX-2 and related molecular targets in the...

The decade since the first Handbook on Hyperbaric Medicine has seen major advances: studies have clarified the actions of hyperbaric oxygenation; clinical practice is becoming more scientific; various organisational and operational guidelines are now widely accepted. This new Handbook arises from the EU Co-operation in Science and Technology...

This comprehensive and easy-to-read monograph is an authoritative update on clinical prostate cancer. It has been prepared by an international, multidisciplinary team at the invitation of the International Prostate Health Council think tank. A particular strength of the book is its presentation of the therapeutic options for patients with...

This book is a snapshot of current research in multiscale modeling, computations and applications. It covers fundamental mathematical theory, numerical algorithms as well as practical computational advice for analysing single and multiphysics models containing a variety of scales in time and space. Complex fluids, porous media flow and...

Bilevel programming problems are hierarchical optimization problems where the constraints of one problem (the so-called upper level problem) are defined in part by a second parametric optimization problem (the lower level problem). If the lower level problem has a unique optimal solution for all parameter values, this problem is equivalent to...

This book contains a broad survey on the peroxiredoxins. It involves almost all groups that contributed significant insights into the emerging field. Coverage discusses the diverse biological roles of the new protein family in the context of other antioxidant systems like those based on heme or selenium catalysis. In addition, the book...

This text covers every aspect of musculoskeletal system rehabilitation. It extends even further into such topics as alternative medicine, holistic therapies, acupuncture, neurophysiologic testing, overuse injuries, work assessment, and outcome measures. Each chapter covers the basic science of the subject, clinical assessments as well as...

The multiplicity of cardiological tests and therapeutical procedures demands a sound knowledge of cardiological English and can be extremely demanding for non-native English speaking cardiologists, cardiology residents, nurses, and medical students. This book is an introduction to cardiological English and intends to help all those who need...

MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor...

An exhaustive treatment of a phenomenon that causes family tragedy worldwide, this book fills a major gap in the current literature. Despite advances in neonatal care, neonatal cerebral injury remains a major cause of morbidity, mortality and disabilities. Cranial ultrasonography provides information on brain maturation in the (preterm)...

Football is probably the most widespread sport in the world. Like many other sports football has undergone major changes. It has increased in intensity, speed, and other factors contributing to increased risks of traumatic injury. Footballers, trainers, and the sport's medical staff are asking for greater information on the traumatic...