Infection is a major cause of morbidity and mortality in patients with neoplastic disease because of compromised host defenses. These defects result in an increased risk of infection and its complications. The nature of the underlying malignancy, the immunodeficiencies associated with it, and the treatments directed against it are all...
about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth...
The human body contains many specialized tissues that are capable of fulfilling an incredible variety of functions necessary for our survival. This volume in the Human Cell Culture Series focuses on mesenchymal tissues and cells. The in vitro study of mesenchymal cells is perhaps the oldest form of human cell culture, beginning with the...
One hundred years ago – in 1899 – Emil Kraepelin, Professor of Psychiatry in Heidelberg and later in Munich – created, in two very important pieces of work, the concept of "manisch-depressives Irresein" ("manic-depressive insanity"). The first was entitled Die klinische Stellung der Melancholie(The...
This is the extensively revised 4th edition of a popular handbook It offers a successful combination of sound educational principles, a how-to-do-it approach and an entertaining easy-to-read style, and contains numerous illustrations, examples, and pertinent cartoons. This fourth edition has been revised to reflect the major changes that...
This book covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer. The current edition attempts to examine the current status of the basic scientific and clinical research in the area, and is a very...
Coronary heart disease (CHD) remains a major cause of human mortality and morbidity worldwide. Classical risk factors for atherosclerosis fail to account fully for the wide variations in CHD prevalence and/or severity between differing populations. The search for hitherto unrecognised risk factors has recently focused on the potential role of...
Glomerulonephritis is one of the commonest causes of end-stage renal failure worldwide. Although there have been considerable advances in the management of renal failure by dialysis and transplantation, there has been relatively little progress in its prevention. This volume sets out to review current practice in the treatment of...
In examining the preface of our first book, it is increases needed. The Deming philosophy empha apparent that the editorial comments made in sizes that quality is never fully achieved: process 1994 are even more pertinent in today's cost- improvement is never ending. constrained healthcare environment than when But, what is quality?...
`Rather than being an esoteric aspect of brain function, lateralization is a fundamental characteristic of the vertebrate brain essential to a broad range of neural and behavioral processes.' Professor Lesley J. Rogers, Chapter 1 of Side Bias: ANeuropsychological Perspective. This volume contains 14 chapters from a...
The Transactions on Pattern Languages of Programming subline aims to publish papers on patterns and pattern languages as applied to software design, development, and use, throughout all phases of the software life cycle, from requirements and design to implementation, maintenance and evolution. The primary focus of this LNCS Transactions...
The 8th volume of ToPNoC contains revised and extended versions of a selection of the best workshop papers presented at the 33rd International Conference on Application and Theory of Petri Nets and Other Models of Concurrency (Petri Nets 2012). The 10 papers cover a diverse range of topics including model checking and system verification,...
