Here, expert scientists from industry and academia share their knowledge on the assembly of functional human tissues in vitro and how to design drug screenings predictive of human exposure. In so doing, they combine the latest technological developments with strategic outlooks, such as novel cell and tissue systems for drug screening and...
This second, completely updated and extended edition of the only reference work in this growing field of medical physics focuses on biomagnetic instrumentation as well as applications in cardiology and neurology. New chapters have been added on fetal magnetography and magnetic field therapy, as well as the safety aspects of magnetic...
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical...
This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology.
The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The...
This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system.
Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. The first reference devoted to the topic, this up-to-date resource covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the...
Toxicogenomics is a new, dynamic and very promising field that can help optimize toxicity analyses and streamline research into active substances. It is of interest not only for basic research and development, but also from a legal and ethical perspective. Here, experts from all the fields mentioned will find solid information provided by an...
This beautifully illustrated monograph provides an up-to-date and comprehensive overview about all fields of liver and biliary tract surgery and liver transplantation. It consists of four sections with 48 chapters: Section I: Anatomy, physiology, imaging and general principles, Section II: Biliary tract surgery, Section III: Liver surgery and...
Discovered over a century ago, the centrosome is the major microtubule organizing center of the animal cell. It is a tiny organelle of surprising structural complexity. Over the last few years our understanding of the structure and composition of centrosomes has greatly advanced, and the demonstration of frequent centrosome anomalies in most...
This is the second part in a two-volume work on neuromodulation. It describes the techniques and procedures applied by direct contact with the central nervous system or cranial nerves (in order to modulate the function of neural networks) or in deeply located structures inside the nervous system (in order to alter the function on specific...
This volume contains 93 papers from internationally recognized experts in the field of brain edema and brain injury. The papers include human and animal studies on edema following stroke, cerebral hemorrhage, traumatic brain injury, spinal cord injury and hydrocephalus. Papers also address fluid dynamics in the brain (including the role of...
Streaming media is one of the most exciting and active research topics with continuing significant progress in the multimedia area, where streaming media has been experiencing dramatic growth and stepped into mainstream media communications.
Streaming Media Architectures, Techniques, and Applications: Recent Advances spans a...
