This book by the International Game Developers Association (IGDA) Game Writing Special Interest Group focuses on various aspects of working as a professional game writer, including how to break in to game writing, writing manuals, narrative design, writing in a team, working as a freelancer, working with new intellectual property, and more....

The intestine is the front line of the confrontation between pathogens and the immune system. However, it is also important to emphasize that we have a symbiotic relationship with innumerable bacteria in the intestine. In the gastrointestinal tract of mammals the lower intestine harbors around 1,000 12 species of anaerobic and aerobic...

This book contains an up-to-date review of diagnostic and staging tools of cholangiocarcinoma, a guide to optimal selection of therapeutic modalities and a review of long-term outcome of surgery and liver transplantation. It also provides surgical techniques and principles for curative and palliative surgery. This book will appeal to...

Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. This book provides detailed and updated information on the role of these molecules in cancer. It is the first to summarize current knowledge of the importance of protein precursors maturation by the convertases in tumor...

The importance of equational axioms emerged initially with the axiomatic approach to Boolean algebras, groups, and rings, and later in lattices. This unique research monograph systematically presents minimal equational axiom-systems for various lattice-related algebras, regardless of whether they are given in terms of join and meet or other...

Over the past decades many surgical subspecialties have moved from traditionally open procedures towards minimally invasive approaches. With the advent of improved technology and smaller more maneuverable devices more delicate procedures have been developed. In this volume the most common neuroendovascular procedures currently practiced are...

The last two decades have shown that the local microenvironment plays a pivotal role in cancer progression. Cancer is not the result of mutation events in single cells, but of a complex interplay of tumor cells, inflammatory cells, stem cells, growth factors, cytokines, chemokines and DNA-damaging agents. This book provides an up-to-date...