A timely primer on the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include...

The world of IT is always evolving, but in every area there are stable, core concepts that anyone just setting out needed to know last year, needs to know this year, and will still need to know next year. The purpose of the Foundations series is to identify these concepts and present them in a way that gives you the strongest...

This book is the definitive and most comprehensive guide to modeling derivatives in C++ today. Providing readers with not only the theory and math behind the models, as well as the fundamental concepts of financial engineering, but also actual robust object-oriented C++ code, this is a practical introduction to the most important derivative...

It is indeed a pleasure to prepare the foreword for vidual surgeons. In addition, it can be read from this text, mainly because I am now a senior ortho- front to back as a history of orthopedics. We are pedist who has known so many of the great ortho- all indebted to S. B. Mosto? for this fascinating pedists who are described in such great...

Beginning .NET Game Programming in VB .NET presents the work of David Weller (.NET Game evangelist at Microsoft) and a group of key Microsoft insiders who decided to write the ideal introduction to game programming for VB .NET programmers. Weller has switched his previous book to VB .NET and added a bonus chapter. The book...