Endomicroscopy is a newly developed diagnostic tool that enables in vivo microscopy with subcellular resolution during ongoing endoscopy in the upper and lower gastrointestinal tract. It is a revolutionary technology. Endoscopy and pathology are no longer separate subjects and, as a result, endomicroscopy leads to a close interaction between...

Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat...

Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that...

Botnet Detection: Countering the Largest Security Threat, a contributed volume by world-class...

Today’s business leaders agree that effectively managing and leveraging information to make decisions has never been more important. More than 60 percent of CEOs feel their organizations need to do better at leveraging their information (IBM® Attributes and Capabilities Study, 2005). CFOs feel that if they leverage their information...

Jitter, noise, and bit error (JNB) and signal integrity (SI) have become today‘s greatest challenges in high-speed digital design. Now, there’s a...

Chest sonography is an established procedure in the stepwise imaging diagnosis of pulmonary and pleural disease. It is the method of choice to distinguish between solid and liquid lesions and allows the investigator to make an unequivocal diagnosis without exposing the patient to costly and stressful procedures. This book presents the state...